Rune Ehrenreich Kuhre
Section for Translational Metabolic Physiology
Blegdamsvej 3, 2200 København N
My primary field of research is within gastrointestinal physiology with particular focus on the mechanisms underlying gastrointestinal hormone release. For the most part, my work is focused on studying the mechanisms of the incretin (insulin stimulating) hormone glucagon-like peptide-1 (GLP-1). I study this by perfused rat intestine studies, which have intact cell polarity and contact with physiological cell neighbors, nerves and vasculature, but at the same time allows strict control of the components of exposure, and by studies on GLP-1 producing cell lines, allowing investigation of ‘L-cell’ molecular biology such as gene expression, gene knock down and fluorescence microscopy.